General description

Absorbance (10%, H₂O, 290 nm):≤0.25.

Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12.

Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state (absorbance: ﹤0.25 at 290 nm, 10% H₂O; aggregation number: 3-12; CMC: 2-6 mM; micellar weight: 1200-4900; pK_a: 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).

Legal Information

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Pai, R., et al. Mol. Biol. Cell15, 2156.

Packaging

5, 25 g in Glass bottle

Preparation Note

Do not use with Mn²⁺ in solution.

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. Discard if bacterial or fungal growth is observed.

Warning

Toxicity: Harmful (C)

aggregation number	3-12, 3 - 12
assay	≥99% (TLC)
CMC	2-6 mM (20-25°C), 2 - 6 mM
color	white
form	solid
HLB	16
InChI key	FHHPUSMSKHSNKW-SMOYURAASA-M
InChI	1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
manufacturer/tradename	Calbiochem^®
mol wt	micellar wt 1200-4900, micellar avg mol wt 1200-5000
pKa	6.2
Quality Level	100
shipped in	ambient
SMILES string	[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
storage condition	desiccated (hygroscopic), OK to freeze
storage temp.	15-25°C